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Reviewed on Jan 30, 2026. by Dr Alexandra Cristina Cowell Writer & Clinical Content Reviewer Next review due on December 22, 2028.
Dr Alexandra Cristina Cowell

Last updated on Jan 30, 2026.

Anti-androgen tablets reduce and thin out excess hair.

  • Spironolactone is a tablet that blocks androgen receptors and reduces androgen production. Androgens are ‘male’ hormones that can cause excess hair growth on the face, chest, and back.

  • It’s prescribed off-label for hirsutism, which just means that while it’s thought to be a safe and effective treatment, it isn’t officially licensed for this purpose.

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50mg
$104.95
  • Prices include:
    Express shipping

    2-5 day shipping by secure courier

  • Consultation + Access to our clinicians

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  • Total
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Spironolactone Spironolactone

What is Spironolactone?

Spironolactone is an anti-androgen tablet that can be used to thin out excess hair growth in male-pattern areas like the face, chest and back – and slow down the growth of new hair. It’s a long-term treatment that you’ll take over a number of months for hirsutism.

How does Spironolactone work?

Spironolactone blocks the effects of androgens and decreases the rate of their production.1,2 Androgens are hormones that drive typically male characteristics like facial hair and a deep voice (testosterone is the main one). These can directly cause excess hair growth on your face, chest, and back. By limiting their production and blocking their effects, Spironolactone thins out any existing hair in these areas, and slows the growth of more.

How do Spironolactone doses work?

Spironolactone comes in a few different doses to treat different conditions: 25 mg, 50 mg, and 100 mg. For hirsutism you’ll normally take the 50 mg tablet, which is the only dose we offer for this condition.

What is the active ingredient in Spironolactone?

Spironolactone is a generic medicine that’s named after its active ingredient, spironolactone. It can be used to treat heart problems, high blood pressure, and fluid retention – as well as being prescribed off-label for hirsutism.

Treated trusted source:

  1. British Association of Dermatologists. (2022). Spironolactone. November.
  2. Cumming, D.C. (1990). Use of spironolactone in treatment of hirsutism. Cleveland Clinic Journal of Medicine. 57(3). pp. 285-287.
Dr Alexandra Cristina Cowell
This page was medically reviewed by Dr Alexandra Cristina Cowell on December 22, 2025. Next review due on December 22, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Spironolactone Spironolactone

How to take Spironolactone

Always follow your prescribing physician’s instructions when taking Spironolactone. Usually, you’ll take one tablet every day with a drink of water after eating. It’s a long-term treatment, and you’ll typically take it for six to twelve months (or sometimes longer) to manage symptoms of hirsutism.

Dr Alexandra Cristina Cowell
This page was medically reviewed by Dr Alexandra Cristina Cowell on December 22, 2025. Next review due on December 22, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Spironolactone Spironolactone

Spironolactone isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.

Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.

Spironolactone Spironolactone

Spironolactone: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

Are there any alternatives to Spironolactone?

Answer:
Yes, there are other options available to manage hirsutism. Oral contraceptives can be useful if you’re looking for a birth control treatment as well as hirsutism treatment, as the hormones in them can decrease the production of androgens.

If you’re looking for a similar treatment to Spironolactone, Flutamide is another anti-androgen that blocks the effects of male hormones. So if Spironolactone isn’t right for you, it could be a suitable alternative.

The only FDA-approved treatments for hirsutism are eflornithine (brand name Vaniqa, now discontinued), electrolysis and laser hair removal. The latter two involve destroying hair follicles with an electrical current, or using light to damage the hair follicles. But these can be painful, invasive, and permanent – so off-label anti-androgen treatments might be more desirable alternatives.

How effective is Spironolactone for hirsutism?

Answer:
Spironolactone has proven to be an effective treatment for hirsutism in clinical studies, which is why it’s prescribed off-label to manage it. Research shows that women who use spironolactone for hirsutism have no further hair darkening and coarsening, a slowed growth rate of any existing hair, and reduced thickness of hair in male-pattern areas.[1]

How long does it take Spironolactone to work for hirsutism?

Answer:
Spironolactone is a long-term treatment for hirsutism. It can take up to six months before you notice any improvement to hair growth and thickness.[2]

Do I need a prescription for Spironolactone?

Answer:
Yes, a doctor will need to make sure Spironolactone is the right treatment for you before you use it. You may also need to undergo regular blood tests to check the levels of potassium in your blood and your kidney function, as Sprinolactone can cause hyperkalemia (dangerously high potassium levels). This can lead to heart problems if untreated.

What should I do if I make a mistake when taking Spironolactone?

Answer:
If you forget to take Spironolactone, you can take the missed tablet as soon as you remember – unless it’s almost time for your next dose. In this case, skip the missed tablet, and carry on as normal from your upcoming dose. Don’t take a double dose to make up for a missed one.

If you accidentally take too much spironolactone, contact your doctor or seek medical attention right away. You may experience:

  • Drowziness

  • Dizziness

  • Dehydration

  • Confusion

  • Nausea

  • Vomiting

  • Diarrhea

  • Skin rashes

  • Weakness

  • Tingling, prickling, or numbness in your skin

  • Muscle spasms

Does Spironolactone cause side effects?

Answer:
Like any medicine, Spironolactone comes with a risk of side effects. They’re very rare, but if you get any of the following, stop taking Spironolactone and contact your doctor right away:

  • Itchiness and blistering of the skin

  • Red or purple rash

  • Detachment of the top layer of skin from lower layers of skin

  • Fever and swelling

  • Yellow skin and eyes

  • Impairment of liver function

  • Irregular heartbeat

  • A tingling sensation

  • Loss of muscle function

  • Difficulty breathing


The most common side effect of Spironolactone, affecting more than one in 10 people, is raised levels of potassium in the blood.

Other common side effects, affecting up to one in 10 people, include:

  • Confusion

  • Dizziness

  • Nausea and vomiting

  • Itching skin

  • Rash

  • Muscle cramps

  • Abnormal kidney function

  • Feeling generally unwell


This isn’t a complete list of all the possible side effects linked to Spironolactone. If you have any concerns, or are looking for more information, take a look at the package insert or contact your doctor.

Can I get Spironolactone through private health insurance?

Answer:
Short answer – it depends. You may need to get prior authorization from your insurance provider before they will cover Spironolactone. This means your insurer and doctor will discuss your condition and spironolactone as a treatment, and then the insurance company will determine whether or not they’ll cover it or not. If you don’t get prior authorization before you start treatment, you may have to pay the full cost.

Your insurer may also only cover part of the cost, or only provide coverage if you obtain it from a specific healthcare provider. But if you can’t get Spironolactone through your health insurance, you should still be able to obtain it through an online pharmacy service – just as long as it’s a safe and suitable treatment for you.

Treated trusted source:

  1. Cumming, D.C. (1990). Use of spironolactone in treatment of hirsutism. Cleveland Clinic Journal of Medicine. 57(3). pp. 285-287.
  2. NHS. (2022). Common questions about spironolactone.

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