Solifenacin ®
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Reviewed on Jan 22, 2026. by Dr Alexandra Cristina Cowell Writer & Clinical Content Reviewer Next review due on January 21, 2029.
Dr Alexandra Cristina Cowell

Last updated on Jan 22, 2026.

Helps your bladder hold more.

Solifenacin is an FDA-approved pill to help manage symptoms of an overactive bladder. It’s the generic version of VESIcare, which means they contain the same active ingredient and work in the same way – but Solifenacin can be a cheaper alternative.

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5mg
$144.95
  • Prices include:
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    2-5 day shipping by secure courier

  • Consultation + Access to our clinicians

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Solifenacin Solifenacin

What is Solifenacin?

Solifenacin is a tablet you’ll take every day to treat an overactive bladder. It relaxes the muscles around your bladder walls, which allows it to hold more urine. It also prevents sudden and involuntary bladder contractions. This means you should need to use the bathroom less frequently, and with less urgency.

How does Solifenacin work?

Solifenacin is a type of muscarinic receptor antagonist. Muscarinic receptors are located on the smooth muscle surrounding the walls of your bladder, and tell these muscles to contract when activated by a neurotransmitter called acetylcholine.

Solifenacin binds to these receptors so acetylcholine can’t, which inhibits the contraction of the muscles around your bladder, keeping them relaxed. While relaxing muscles might sound counter-productive if you’re struggling with overactive bladder, it actually means your bladder can hold more urine before you need to go, and helps to prevent sudden, involuntary contractions.[1]

How do Solifenacin doses work?

Solifenacin tablets come in two doses: a 5 mg and 10 mg tablet. You’ll normally start on the 5 mg tablet, and if you’re feeling good with side effects, your doctor might move you up to 10 mg. We only offer the 5 mg tablet, but if your clinician recommends that you move up to 10 mg, you can just take two tablets per dose.

What is Solifenacin’s active ingredient?

Solifenacin is a generic medicine. It’s named after its active ingredient, solifenacin succinate. It’s a time of muscarinic receptor antagonist, which means it binds to muscarinic receptors on the smooth muscle around your bladder to prevent these muscles from contracting. This helps to manage symptoms of overactive bladder, like the frequent and sudden urge to urinate.

Treated trusted source:

  1. Chilman-Blair, K. Bosch, J.L.H.R. (2004). Solifenacin: treatment of overactive bladder. Drugs Today. (Barc.) 40(4). pp. 343-353M
Dr Alexandra Cristina Cowell
This page was medically reviewed by Dr Alexandra Cristina Cowell on January 21, 2026. Next review due on January 21, 2029.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Solifenacin Solifenacin

How to take Solifenacin

Always follow your prescriber’s guidance when taking Solifenacin. You’ll take your prescribed dose of Solifenacin once each day, around the same time each day. You can take it with or without food, so just pick a time that you’ll be able to take it each day – like first thing in the morning, or just before bed. Swallow your tablets whole with a drink of water.

Dr Alexandra Cristina Cowell
This page was medically reviewed by Dr Alexandra Cristina Cowell on January 21, 2026. Next review due on January 21, 2029.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Solifenacin Solifenacin

Solifenacin isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.

Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.

Solifenacin Solifenacin

Solifenacin: FAQ

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

Are there any alternatives to Solifenacin?

Answer:
Yes, you’ve got options to help manage symptoms of overactive bladder. Oxybutynin is really similar to Solifenacin; it’s an antimuscarinic that blocks the neurotransmitter acetylcholine, which is what causes the muscles around your bladder to contract. This means your bladder can hold more urine, and it should prevent the involuntary contractions that make you need to go suddenly and urgently.

Mirabegron is a slightly different option, but works in a similar way. It activates receptors called beta-3 adrenergic receptors in the muscle around your bladder. This allows it to hold more liquid, and reduces the sudden need to urinate associated with overactive bladder. Because the way it works is different to Solifenacin, it can come with a lower risk of side effects like dry mouth, constipation, and blurred vision – but can come with a risk of increased blood pressure.

How effective is Solifenacin for overactive bladder?

Answer:
Solifenacin has been clinically proven as an effective treatment for managing symptoms of overactive bladder. One study comparing Solifenacin 5mg to placebo found that 29% of participants had no urgency episodes after treatment, compared to 15% in the placebo group. 51% of people also reported no incontinence episodes at the end of the study, compared to 34% in the placebo group. Significantly more people taking Solifenacin also reported that how often they needed to urinate had normalised.[1]

Do I need a prescription for Solifenacin?

Answer:
Yes. Solifenacin is a prescription-only medicine, meaning a healthcare professional will need to check that it’s the right treatment for you before you can use it. For example, it might not be suitable for people with liver or kidney disease, if you have urinary retention, or severe stomach or bowel conditions.

What should I do if I make a mistake when taking Solifenacin?

Answer:
If you take more Solifenacin than you’ve been told to, get medical attention right away. You may experience symptoms like:

  • Headache

  • Dry mouth

  • Dizziness

  • Drowsiness

  • Blurred vision

  • Hallucinations

  • Over-excitability

  • Seizures

  • Difficulty breathing

  • Elevated heart rate

  • Urinary retention

  • Dilated pupils


If you miss a dose of Solifenacin, take it as soon as you remember. But if it’s almost time for your next dose, skip the one you missed and carry on as normal from your next scheduled pill. Never take a double dose of Solifenacin to make up for missing one.

How long does it take Solifenacin to work for overactive bladder?

Answer:
Solifenacin will get to work within three to six hours of taking it. But it’s a long-term treatment, and it can be between four and six weeks before you get the full benefits of treatment.[2]

Does Solifenacin cause side effects?

Answer:
Like any medicine you take, Solifenacin comes with some risk of side effects. If you experience any of the following, stop taking Solifenacin right away and get medical attention:

  • Blistering or peeling of the skin

  • Swelling of the tissue just below the skin

  • Difficulty breathing


The most common side effect of Solifenacin, which affects more than one in ten people, is dry mouth. Other common side effects (affecting up to one in ten people) are:

  • Blurred vision

  • Constipation

  • Nausea

  • Indigestion

  • Stomach discomfort

  • Bloating

  • Burping

  • Heartburn


This isn’t a comprehensive list of all of the side effects associated with Solifenacin. If you have any questions or concerns, take a look at the patient package insert, or get in touch with your healthcare provider.

Can I get Solifenacin through private health insurance?

Answer:
If you’ve been prescribed Solifenacin for overactive bladder, most health insurance plans (like Medicare) should offer coverage for your treatment. But it’s always best to check your insurer’s formulary (the medicines they cover), and get in touch with them to see if you need prior authorization. This is a conversation between your prescriber and insurance company so they can check the treatment they’re covering is a medical necessity.

Your insurance provider may only cover part of the cost of treatment, or only offer coverage if you get it from certain healthcare providers, too. But if you can’t get Solifenacin through your health insurance, you should still be able to get it through an online pharmacy service. A healthcare professional will just need to ask some questions to make sure it’s the right treatment for you.

Treated trusted source:

  1. Chapple, C.R. (2006). Solifenacin significantly improves all symptoms of overactive bladder syndrome. International Journal of Clinical Practice. 60(8). pp. 959-966.
  2. NHS. (2024). About solifenacin. Jul 2.

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