What are the best treatments for vaginal yeast infections?
A close look at the best available treatments for vaginal yeast infections, and how to avoid future …
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Last updated on Mar 03, 2025.
Monistat is a vaginal cream and suppository for yeast infections.
It’s available in three doses for personalized care.
Monistat is the branded version of Miconazole.
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Monistat is a vaginal cream containing an antifungal to help treat yeast infections. You can get it as a dual treatment containing a vaginal suppository or ovule (that come with an applicator as well or are prefilled into an applicator) with an external cream for itch relief.
A yeast infection (also known as vaginal thrush) is caused by the overgrowth of yeast in the vagina. This causes symptoms like itching, burning and abnormal vaginal discharge, but it can also be asymptomatic, meaning it doesn’t present any symptoms.[1]
You don’t always require treatment for a yeast infection, as it can resolve on its own. But if the symptoms persist, you’ll need topical or oral antifungal medication.
Miconazole is an antifungal that reduces the fungi’s ability to produce ergosterol, a key part of the cell wall. Without it, the fungi weakens, making it easier for your immune system to clear the infection.[2]
There are three versions of Monistat available:
The suppository and ovule are inserted into your vagina to help clear the infection. You can also get each treatment with an external vaginal cream that’s used to relieve itching and irritation.
The dose you choose depends on the severity of your infection, as well as your health needs and preferences.

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When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Depending on the version you use, the instructions will vary. It’s best to read the instructions that come with your medicine before using it.
How to use Monistat suppository
How to use Monistat ovule
How to use Monistat applicator
Prefilled applicator:
If the applicator isn’t pre-filled, follow the instructions below:
How to use vaginal cream
If you’re unsure what to do, check the package leaflet that comes with your medicine. It will have detailed instructions with pictures. If you’re still unsure, you can contact our clinicians online.
Depending on the treatment, the dosage will vary. Monistat 1 is a one-dose treatment, while Monistat 3 is used for three days and Monistat 7 for seven days.
The external vaginal cream can be used twice a day (morning and night) for up to seven days, even if you’re using Monistat 1.
Your symptoms should start to lessen within a day and completely clear within a few days.
It can take a little longer if you’re using Monistat 3 or 7, as they contain a lower dose of the antifungal miconazole.

How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Monistat isn’t suitable for everyone, and there are some things that you need to be aware of when using it.
Here’s all the official info on it. If anything is unclear, let our physician know, and they can talk with you about it.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Last updated on Mar 03, 2025.
Our experts continually monitor new findings in health and medicine, and we update our articles when new info becomes available.
Mar 03, 2025
Published by: The Treated Content Team. Medically reviewed by: Dr Alexandra Cristina Cowell, Writer & Clinical Content ReviewerHow we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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A close look at the best available treatments for vaginal yeast infections, and how to avoid future …
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Cristina writes content for Treated, and reviews content produced by our other writers to make sure it’s clinically accurate.
Meet Alexandra CristinaHow we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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