What are the best treatments for vaginal yeast infections?
A close look at the best available treatments for vaginal yeast infections, and how to avoid future …
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Last updated on Mar 02, 2025.
Clotrimazole is a cream for vaginal yeast infections.
Clotrimazole is an antifungal treatment you use to treat yeast infections (also known as vaginal thrush). Clotrimazole Cream 1% is used to treat fungal skin infections, including thrush, and relieves irritation.
Yeast infections are caused by an overgrowth of yeast cells called candida in your vagina and/or vulva. Clotrimazole targets the yeast cells and kills off the infection, relieving your symptoms.
Clotrimazole works by targeting the yeast that causes the infections. The active ingredient in Clotrimazole, clotrimazole, is a powerful antifungal treatment. It damagesthe outer membrane of each yeast cell by blocking the yeast cells from producing ergosterol, which is a substance that serves the same function cholesterol does in the human body.[1]
Ergosterol keeps the yeast cells alive and helps them reproduce. Clotrimazole cream works locally in your vagina. It also helps to relieve itchiness and irritation. It kills off the yeast cells there and limits their growth, curing your yeast infection.
Clotrimazole cream is available in one dose (1%). You will usually only need to use the medication for up to seven days. If it has been seven days since you started your treatment and your infection is still around, get in touch with a medical provider. You may need a different course of treatment. If you’ve had more than two instances of vaginal yeast infection in six months, tell a doctor. There may be something else causing your infection to keep coming back.

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When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Always use your Clotrimazole cream as your physician tells you to.
Most of the symptoms of your infection should clear within a couple of days. So things like itching, redness and discharge should vanish pretty quickly. The yeast cells will need to be combatted fully so that your infection won’t come back again, so you should continue using the cream for the full time your doctor prescribed, even if you start feeling better sooner.
Don’t swallow the cream. If you accidentally get it in your mouth or swallow it, seek medical attention right away.
If you forget to use the cream, apply it as soon as possible and complete your treatment. Try not to scratch the area as the infection will spread, and keep the area clean. Always wash your hands after using the cream.

How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Clotrimazole isn’t suitable for everyone, and there are some things that you need to be aware of when using it.
Here’s all the official info on it. If anything is unclear, let a doctor know, and they can talk with you about it.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Last updated on Mar 02, 2025.
Our experts continually monitor new findings in health and medicine, and we update our articles when new info becomes available.
Mar 02, 2025
Published by: The Treated Content Team. Medically reviewed by: Dr. Joseph Palumbo, Senior Medical AdviserHow we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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A close look at the best available treatments for vaginal yeast infections, and how to avoid future …
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Joseph joined Treated in 2023, and is one of the lead doctors providing prescribing services for the platform.
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