Astelin is an antihistamine that helps relieve the symptoms of a nasal infection.
Nasal infections can happen for various reasons, like colds or bacteria. Most of the time, nasal infections are self-limiting, meaning they clear up on their own without any treatment.
But when you do get a nasal infection, your immune system releases histamine to fight off the infection. Histamine is a useful part of the immune response, but it can also cause uncomfortable effects like inflammation, which leads to blocked and runny nose.
Astelin helps stop histamine from being released, which helps alleviate these symptoms.
How does Astelin work?
Azelastine, the active ingredient in Astelin, is an antihistamine that prevents histamine from binding to receptors in your nose.
Histamine is a chemical that’s often released as part of your immune response to an allergen or foreign invader, like bacteria. While histamine plays a role in helping to fight the infection, it can trigger symptoms like nasal congestion, making it difficult to breathe and being generally uncomfortable.
By blocking histamine Astelin reduces inflammation, which in turn alleviates these symptoms.[1]
What doses of Astelin are there?
Astelin is available as a nasal spray in 0.1% concentration. The usual dose is one to two sprays in each nostril, once a day. For serious infections, you might need to use it twice a day, but your doctor will provide detailed information on the dosage after your consultation.
This page was written by The Treated Content Team.
This page was medically reviewed by Dr. Joseph Palumbo on January 23, 2025. Next review due on January 23, 2028.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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How to use Astelin
Before using Astelin, you’ll need to first prime the bottle:
Shake the bottle.
Remove the cap.
Press the pump multiple times until a fine mist is produced.
After that, it’s ready to use. To use Astelin:
Blow your nose gently.
Remove the cap.
Spray once into your nostril while keeping your head upright.
Repeat for the other nostril.
Wipe and replace the protective cap.
You should only use Astelin once a day unless your doctor advises otherwise.
How long does Astelin take to work?
Astelin works relatively quickly (within 15 to 30 minutes). You should notice an improvement in your symptoms and find it easier to breathe through your nose.
If you accidentally use more than the recommended amount, you’re unlikely to get any side effects. But if you are concerned, you can contact your doctor anytime.
This page was written by The Treated Content Team.
This page was medically reviewed by Dr. Joseph Palumbo on January 23, 2025. Next review due on January 23, 2028.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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Astelin isn’t suitable for everyone, and there are some things that you need to be aware of when using it.
Here’s all the official info on it. If anything is unclear, let our doctor know, and they can talk with you about it.
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Astelin: FAQ
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Is there a generic version of Astelin?
Answer:
Yes, Astelin is the branded version of azelastine. Both treatments contain the same active ingredient, azelastine hydrochloride, and are available as a nasal spray. According to the FDA, the generic version is just as effective as the branded one, so there should be no significant difference.[1]
However, azelastine is available in two concentrations: a lower dose of 0.05% and a higher dose of 0.1%. This allows for more flexibility in tailoring the treatment to your specific needs, unlike Astelin, which only comes in one concentration. Additionally, the packaging and prices differ, with the generic version typically being cheaper.
Is Astelin available over the counter?
Answer:
No, Astelin is only available with a prescription from a doctor. This is so they can check it's safe and suitable for you. Your doctor will then review your case, and prescribe it if they deem it suitable.
How does Astelin differ from other medications for nasal infection?
Answer:
Nasal infections often resolve on their own and may not require treatment. But if the symptoms interfere with your daily life, using a nasal spray can help until the infection clears.
There are many types of nasal sprays available, such as antihistamine nasal sprays (like Astelin), or corticosteroid sprays, like Nasonex. Each spray works differently to relieve symptoms. For instance, Astelin blocks histamine from binding to its receptors, while Nasonex helps calm your immune response and reduces swelling. The one you use is yours to choose, but if you're unsure your doctor can help you.
Will I get side effects using Astelin?
Answer:
Although you're unlikely to experience side effects while using Astelin, there's a chance of experiencing them. Some side effects include:
Unpleasant aftertaste in your mouth.
Nose irritation.
Sneezing.
Nose bleeds.
For the full list of side effects check the package insert.
Our experts continually monitor new findings in health and medicine, and we update our articles when new info becomes available.
Jan 22, 2025
Published by: The Treated Content Team.Medically reviewed by: Dr. Joseph Palumbo, Senior Medical Adviser
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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Dr. Joseph Palumbo
Senior Medical Adviser
Joseph joined Treated in 2023, and is one of the lead doctors providing prescribing services for the platform.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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